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Publications

2023

Dong F, Jumper MBE, Becker-Haimes EM, Vatza C, Miao LL, Conroy C, Bennett M, Sarpal DK, Abegunde C, Kohler CG, Calkins ME. Tele-mental Health Transitions for Pennsylvania Coordinated Specialty Care Programs for Early Psychosis During the COVID-19 Pandemic. Psychiatr Q. 2023 Feb 23:1–14. doi: 10.1007/s11126-023-10015-0. Epub ahead of print. PMID: 36820952; PMCID: PMC9947877. PubMed Link

2022

Myers N, Hutnyan M, Daley TC, Bello I, Chacon M, Currie A, Davis BJ, Dixon LB, George PE, Giannicchi A, Kwashie AN, McCormick KA, Meyer-Kalos P, Nagendra A, Nayar S, Sarpal DK, Sepahpour TY, Shapiro DI, Taylor-Zoghby J. Pathways Through Early Psychosis Care for U.S. Youths From Ethnically and Racially Minoritized Groups: A Systematic Review. Psychiatr Serv. 2023 Feb 15:appips20220121. doi: 10.1176/appi.ps.20220121. Epub ahead of print. PMID: 36789610 PubMed Link

 

Mayeli A, Sonnenschein SF, Yushmanov VE, Wilson JD, Blazer A, Foran W, Perica M, Calabro FJ, Luna B, Hetherington HP, Sarpal DK, Ferrarelli F. Dorsolateral Prefrontal Cortex Glutamate/Gamma-Aminobutyric Acid (GABA) Alterations in Clinical High Risk and First-Episode Schizophrenia: A Preliminary 7-T Magnetic Resonance Spectroscopy Imaging Study. Int J Mol Sci. 2022 Dec 13;23(24):15846. doi: 10.3390/ijms232415846. PMID: 36555487; PMCID: PMC9781166 PubMed Link

 

Sonnenschein SF, Mayeli A, Yushmanov VE, Blazer A, Calabro FJ, Perica M, Foran W, Luna B, Hetherington HP, Ferrarelli F, Sarpal DK. A longitudinal investigation of GABA, glutamate, and glutamine across the insula during antipsychotic treatment of first-episode schizophrenia. Schizophr Res. 2022 Oct;248:98-106. doi: 10.1016/j.schres.2022.08.008. Epub 2022 Aug 24. PMID: 36029656 PubMed Link

 

Sonnenschein SF, Parr AC, Larsen B, Calabro FJ, Foran W, Eack SM, Luna B, Sarpal DK. Subcortical brain iron deposition in individuals with schizophrenia. J Psychiatr Res. 2022 Jul;151:272-278. doi: 10.1016/j.jpsychires.2022.04.013. Epub 2022 Apr 28. PMID: 35523067 PubMed Link

 

Blazer A, Chengappa KNR, Foran W, Parr AC, Kahn CE, Luna B, Sarpal DK. Changes in corticostriatal connectivity and striatal tissue iron associated with efficacy of clozapine for treatment‑resistant schizophrenia. Psychopharmacology (Berl). 2022 Aug;239(8):2503-2514. doi: 10.1007/s00213-022-06138-0. Epub 2022 Apr 18. PMID: 35435461; PMCID: PMC9013738 PubMed Link

 

Sarpal DK, Blazer A, Wilson JD, Calabro FJ, Foran W, Kahn CE, Luna B, Chengappa KNR. Relationship between plasma clozapine/N-desmethylclozapine and changes in basal forebrain-dorsolateral prefrontal cortex coupling in treatment- resistant schizophrenia. Schizophr Res. 2022 May;243:170-177. doi: 10.1016/j.schres.2022.03.014. Epub 2022 Apr 2. PMID: 35381515; PMCID: PMC9189030 PubMed Link

2021

Esque J, Rasmussen A, Spada M, Gopalan P, Sarpal D. First-Episode Psychosis and the Role of the Psychiatric Consultant. J Acad Consult Liaison Psychiatry. 2022 Jan-Feb;63(1):32-35. doi: 10.1016/j.jaclp.2021.07.003. Epub 2021 Jul 26. PMID: 34325090 PubMed Link

2020

Westfall MBE, Kohler CG, Hurford I, Abegunde C, Agosti D, Brinen A, Cadman ML, Conroy C, Ered A, Fooks A, Franco O, Huque ZM, Namowicz D, O’Connor S, Oross M, Payne E, Sarpal DK, Schmidt LR, Swigart A, Wenzel RM, Calkins ME. Pennsylvania coordinated specialty care programs for first-episode psychosis: 6- and 12-month outcomes. Early Interv Psychiatry. 2021 Oct;15(5):1395-1408. doi: 10.1111/eip.13084. Epub 2020 Dec 6. PMID: 33283472 PubMed Link

 

Sarpal DK, Tarcijonas G, Calabro FJ, Foran W, Haas GL, Luna B, Murty VP. Context-specific abnormalities of the central executive network in first-episode psychosis: relationship with cognition. Psychol Med. 2022 Sep;52(12):2299-2308. doi: 10.1017/S0033291720004201. Epub 2020 Nov 23. PMID: 33222723; PMCID: PMC9805803 PubMed Link

 

Wood HJ, Gannon JM, Chengappa KNR, Sarpal DK. Group teletherapy for first- episode psychosis: Piloting its integration with coordinated specialty care during the COVID-19 pandemic. Psychol Psychother. 2021 Jun;94(2):382-389. doi: 10.1111/papt.12310. Epub 2020 Oct 20. PMID: 33078496 PubMed Link

 

Blair Thies M, DeRosse P, Sarpal DK, Argyelan M, Fales CL, Gallego JA, Robinson DG, Lencz T, Homan P, Malhotra AK. Interaction of Cannabis Use Disorder and Striatal Connectivity in Antipsychotic Treatment Response. Schizophr Bull Open. 2020 Jan;1(1):sgaa014. doi: 10.1093/schizbullopen/sgaa014. Epub 2020 Mar 20. PMID: 32803161; PMCID: PMC7418867 PubMed Link

 

Nichols J, Gannon JM, Conlogue J, Sarpal D, Montgomery JL, Sherwood R, Fabian T, Ballough JR, Fredrick NM, Chengappa KNR. Ensuring care for clozapine- treated schizophrenia patients during the COVID-19 pandemic. Schizophr Res. 2020 Aug;222:499-500. doi: 10.1016/j.schres.2020.05.053. Epub 2020 May 26. PMID: 32473934; PMCID: PMC7247984 PubMed Link

2019

Tarcijonas G, Foran W, Blazer A, Eack SM, Luna B, Sarpal DK. Independent support for corticopallidal contributions to schizophrenia-related functional impairment. Schizophr Res. 2020 Feb;216:168-174. doi: 10.1016/j.schres.2019.12.006. Epub 2019 Dec 24. PMID: 31882276; PMCID: PMC7239703 PubMed Link

 

Tarcijonas G, Foran W, Haas GL, Luna B, Sarpal DK. Intrinsic Connectivity of the Globus Pallidus: An Uncharted Marker of Functional Prognosis in People With First-Episode Schizophrenia. Schizophr Bull. 2020 Jan 4;46(1):184-192. doi: 10.1093/schbul/sbz034. PMID: 31150557; PMCID: PMC6942165 PubMed Link

 

Barber AD, Sarpal DK, John M, Fales CL, Mostofsky SH, Malhotra AK, Karlsgodt KH, Lencz T; Pediatric Imaging, Neurocognition, and Genetics (PING) Study Consortium. Age-Normative Pathways of Striatal Connectivity Related to Clinical Symptoms in the General Population. Biol Psychiatry. 2019 Jun 1;85(11):966-976. doi: 10.1016/j.biopsych.2019.01.024. Epub 2019 Feb 6. PMID: 30898336; PMCID: PMC6534442 PubMed Link

 

Manivannan A, Foran W, Jalbrzikowski M, Murty VP, Haas GL, Tarcijonas G, Luna B, Sarpal DK. Association Between Duration of Untreated Psychosis and Frontostriatal Connectivity During Maintenance of Visuospatial Working Memory. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 May;4(5):454-461. doi: 10.1016/j.bpsc.2019.01.007. Epub 2019 Jan 30. PMID: 30852127; PMCID: PMC6631364 PubMed Link

 

Tarcijonas G, Sarpal DK. Neuroimaging markers of antipsychotic treatment response in schizophrenia: An overview of magnetic resonance imaging studies. Neurobiol Dis. 2019 Nov;131:104209. doi: 10.1016/j.nbd.2018.06.021. Epub 2018 Jun 25. PMID: 29953933; PMCID: PMC6541531 PubMed Link

2018

Argyelan M, Herzallah M, Sako W, DeLucia I, Sarpal D, Vo A, Fitzpatrick T, Moustafa AA, Eidelberg D, Gluck M. Dopamine modulates striatal response to reward and punishment in patients with Parkinson’s disease: a pharmacological challenge fMRI study. Neuroreport. 2018 May 2;29(7):532-540. doi: 10.1097/WNR.0000000000000970. PMID: 29432300; PMCID: PMC5895508 PubMed Link

2017

Sarpal DK, Robinson DG, Fales C, Lencz T, Argyelan M, Karlsgodt KH, Gallego JA, John M, Kane JM, Szeszko PR, Malhotra AK. Relationship between Duration of Untreated Psychosis and Intrinsic Corticostriatal Connectivity in Patients with Early Phase Schizophrenia. Neuropsychopharmacology. 2017 Oct;42(11):2214-2221. doi: 10.1038/npp.2017.55. Epub 2017 Mar 15. PMID: 28294137; PMCID: PMC5603815 PubMed Link

2016

Sarpal DK, Lencz T, Malhotra AK. In Support of Neuroimaging Biomarkers of Treatment Response in First-Episode Schizophrenia. Am J Psychiatry. 2016 Jul 1;173(7):732-3. doi: 10.1176/appi.ajp.2016.16030320. PMID: 27363555; PMCID: PMC6071671 PubMed Link

 

Argyelan M, Lencz T, Kaliora S, Sarpal DK, Weissman N, Kingsley PB, Malhotra AK, Petrides G. Subgenual cingulate cortical activity predicts the efficacy of electroconvulsive therapy. Transl Psychiatry. 2016 Apr 26;6(4):e789. doi: 10.1038/tp.2016.54. PMID: 27115120; PMCID: PMC4872412 PubMed Link

 

Sarpal DK, Argyelan M, Robinson DG, Szeszko PR, Karlsgodt KH, John M, Weissman N, Gallego JA, Kane JM, Lencz T, Malhotra AK. Baseline Striatal Functional Connectivity as a Predictor of Response to Antipsychotic Drug Treatment. Am J Psychiatry. 2016 Jan;173(1):69-77. doi: 10.1176/appi.ajp.2015.14121571. Epub 2015 Aug 28. PMID: 26315980; PMCID: PMC4845897 PubMed Link

2015

Argyelan M, Gallego JA, Robinson DG, Ikuta T, Sarpal D, John M, Kingsley PB, Kane J, Malhotra AK, Szeszko PR. Abnormal resting state FMRI activity predicts processing speed deficits in first-episode psychosis. Neuropsychopharmacology. 2015 Jun;40(7):1631-9. doi: 10.1038/npp.2015.7. Epub 2015 Jan 8. PMID: 25567423; PMCID: PMC4915267 PubMed Link

 

Sarpal DK, Robinson DG, Lencz T, Argyelan M, Ikuta T, Karlsgodt K, Gallego JA, Kane JM, Szeszko PR, Malhotra AK. Antipsychotic treatment and functional connectivity of the striatum in first-episode schizophrenia. JAMA Psychiatry. 2015 Jan;72(1):5-13. doi: 10.1001/jamapsychiatry.2014.1734. PMID: 25372846; PMCID: PMC4286512 PubMed Link

2014

Wint DP, Butman JA, Masdeu JC, Meyer-Lindenberg A, Mervis CB, Sarpal D, Morris CA, Berman KF. Intracranial arteries in individuals with the elastin gene hemideletion of Williams syndrome. AJNR Am J Neuroradiol. 2014 Jan;35(1):90-4. doi: 10.3174/ajnr.A3641. Epub 2013 Jul 18. PMID: 23868161; PMCID: PMC7966472 PubMed Link

2012

Manu P, Sarpal D, Muir O, Kane JM, Correll CU. When can patients with potentially life-threatening adverse effects be rechallenged with clozapine? A systematic review of the published literature. Schizophr Res. 2012 Feb;134(2-3):180-6. doi: 10.1016/j.schres.2011.10.014. Epub 2011 Nov 22. PMID: 22113154; PMCID: PMC3318984 PubMed Link

2010

Eisenberg DP, Sarpal D, Kohn PD, Meyer-Lindenberg A, Wint D, Kolachana B, Apud J, Weinberger DR, Berman KF. Catechol-o-methyltransferasevaline(158)methionine genotype and resting regional cerebral blood flow in medication-free patients with schizophrenia. Biol Psychiatry. 2010 Feb 1;67(3):287-90. doi: 10.1016/j.biopsych.2009.08.039. Epub 2009 Nov 5. PMID: 19892319; PMCID: PMC2812618 PubMed Link

2008

Sarpal D, Buchsbaum BR, Kohn PD, Kippenhan JS, Mervis CB, Morris CA, Meyer- Lindenberg A, Berman KF. A genetic model for understanding higher order visual processing: functional interactions of the ventral visual stream in Williams syndrome. Cereb Cortex. 2008 Oct;18(10):2402-9. doi: 10.1093/cercor/bhn004. Epub 2008 Feb 27. PMID: 18308711; PMCID: PMC2733313 PubMed Link

2005

Meyer-Lindenberg A, Mervis CB, Sarpal D, Koch P, Steele S, Kohn P, Marenco S, Morris CA, Das S, Kippenhan S, Mattay VS, Weinberger DR, Berman KF. Functional, structural, and metabolic abnormalities of the hippocampal formation in Williams syndrome. J Clin Invest. 2005 Jul;115(7):1888-95. doi: 10.1172/JCI24892. Epub 2005 Jun 9. PMID: 15951840; PMCID: PMC1143592. PubMed Link

2004

Sarpal D, Koenig JI, Adelman JP, Brady D, Prendeville LC, Shepard PD. Regional distribution of SK3 mRNA-containing neurons in the adult and adolescent rat ventral midbrain and their relationship to dopamine-containing cells. Synapse. 2004 Aug;53(2):104-13. doi: 10.1002/syn.20042. PMID: 15170822 PubMed Link